Erythrocytapheresis in a Patient of Sickle Cell Disease Presenting in Crisis.

As per American Society of Apheresis (ASFA) guidelines, the indication for Erythrocytapheresis for sickle cell patients is category III for preoperative management and vaso-occlusive crisis. Erythrocytapheresis, with the help of automated cell separators, has the benefit of reducing the Sickle hemoglobin (HbS) levels to <30.0% with a reduced risk of increasing blood viscosity and single procedure achieving target hemoglobin levels. A 17-year-oldfemale patient who was a known case of sickle cell disease presented to our institution with a vascular necrosis of the right femoral head. Due to the pain and limitations of her day-to-day activities, she was advised for total hip arthroplasty. This patient underwent a successful Erythrocytapheresis using an automated cell separator and was operated on. In a sickle cell patient planned for surgical intervention, the procedure of Erythrocytapheresis can help in decreasing the chances of the patient developing any vaso-occlusive crisis during surgery and in the immediate post-operative period. This technique can help in improving the chances of a successful surgical procedure for such patients.

Recurrent Viral Infections Post COVID 19.

The novel corona virus causing severe acute respiratory symptoms appeared in China at the end of year 2019 and soon spread globally resulting in Pandemic. The susceptibility to novel corona virus infection and severity of symptoms in an individual is an outcome of immune system of the host. The Human leucocyte Antigen (HLA) of an individual is responsible for regulation of immune system. Thus, genetic variability of the HLA can affect the individual's response to Novel corona virus infection in terms of susceptibility and severity. The memory B cells which persist in the body after initial infection protect by faster response to repeat infection by the virus. However viral mutations prevent recognition by memory B cells and therefore repeat infection by virus leads to slow immune response as immunity to the mutated virus is not present.

Health Promoting Lifestyle Profile Assessment among Medical and Nursing Students of Central India.

The Health Promoting Lifestyle Profile-II (HPLP-II) is a western-developed questionnaire that assesses 52 health-promoting behaviours (HPB) over six subscales. The purpose of this research was to identify and assess all six components of the Health-Promoting lifestyle Profile among medical and nursing students in central India (AIIMS and Gandhi Medical College, Bhopal). A cross sectional descriptive study was conducted on 619 medical (MBBS/MD/MS) and nursing students of AIIMS and GMC, Bhopal. The online questionnaires were provided to them which consisted of questions from the Health-Promoting Lifestyle Profile II. Health-promoting behaviors differed by gender in MBBS students particularly with respect to Health-Promoting Lifestyle (p=0.009), Health Responsibility (p=0.021), Nutrition (p=0.046) and Physical Activity (p=0.004). Males had significantly higher scores then females. But the difference between males and females was not significant in PG (MD and MS) students. Scores of five out of six scales (except spiritual growth) were found to be higher among nursing students in comparison with medical students (MBBS, MD and MS). These results will raise concerns about lifestyle behaviours and encourage medical and nursing students to evaluate their own health-promoting lifestyles. Physical exercise and diet should be prioritised, particularly for medical students.